豬非典型瘟病毒（atypical porcine pestivirus，APPV）是2015年新發(fā)現(xiàn)的瘟病毒屬病毒，國(guó)際病毒分類(lèi)學(xué)委員會(huì)2017 年將其確定為瘟病毒屬K（Pestivirus K）的代表毒株。該病毒可導(dǎo)致仔豬先天性震顫（congenital tremor，CT），典型癥狀為仔豬輕微震顫，頭部和四肢明顯。目前APPV已在全球廣泛流行，我國(guó)也有相關(guān)報(bào)道，關(guān)于該病毒研究的報(bào)道越來(lái)越多，但研究進(jìn)展的報(bào)道相對(duì)較少，目前已證實(shí)其與CT緊密相關(guān)。APPV不容易被分離，缺少最重要的病毒攻毒試驗(yàn)結(jié)果，疫苗研究也需要在前期基礎(chǔ)研究深入的基礎(chǔ)上才有可能獲得成功。為此，本文從病原學(xué)、流行病學(xué)、診斷技術(shù)及疫苗研發(fā)等方面，對(duì)取得的最新研究進(jìn)展進(jìn)行概述，以期增強(qiáng)人們對(duì)APPV的認(rèn)識(shí)，為我國(guó)防控與研究APPV提供參考。
Advances in the Researches on Atypical Porcine Pestivirus
Atypical porcine pestivirus（APPV）is a new pestivirus virus firstly detected in 2015，which is determined as the representative strain of pestivirus K by the International Committee on the Taxonomy of Viruses in 2017. Because of the virus，congenital tremor（CT）might occur in piglets with such typical symptoms as slight tremor especially in head and limbs. APPV has been widely prevalent all over the world and also reported in China，but there are few reports related to the advances in relevant researches on the virus although with more reports about the researches. At present，it has been confirmed to be closely related to CT. It is difficult to isolate the virus due to the lack of most important results about virus attack test，and the development on vaccines could be achieved only based on the results of preliminary researches. Therefore，the latest relevant advances were summarized from the aspects of etiology，epidemiology，diagnostic technology and vaccine development，with a view to improving public's awareness for the virus and providing a reference for relevant prevention，control and researches in China.
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